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Medical Scope Journal (MSJ)
Published by Universitas Sam Ratulangi
ISSN : -     EISSN : 27153312     DOI : https://doi.org/10.35790/msj
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Nursing Public Health
Medical Scope Journal (MSJ) diterbitkan oleh Perhimpunan Ahli Anatomi Indonesia (PAAI) Komisariat Manado bekerjasama dengan Fakultas Kedokteran Universitas Sam Ratulangi dua kali setahun pada bulan Juni dan Desember. Tulisan yang dimuat dapat berupa artikel telaah (review article), hasil penelitian, dan laporan kasus dalam bidang ilmu kedokteran baik dalam bahasa Indonesia maupun dalam bahasa Inggris.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 23 Documents
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Search results for , issue "Vol. 6 No. 2 (2024): Medical Scope Journal" : 23 Documents clear
Effectiveness and Outcome of Electronic Medical Record in Patient Service: A Systematic Review Turido Pratama
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.50383

Abstract

Abstract: Using electronic medical records is one endeavor to enhance healthcare services and patient outcomes. The electronic medical record (EMR) is employed in healthcare facilities to accomplish every objective. This studyaimed to  evaluate the effectiveness and effect of medical record usage in hospitals. This was a systematic review study. Three databases—PubMed, ScienceDirect, and Cochrane—were searched for research publications in this study. Publications published during the last ten years were targeted for search. Three reviewers were involved in the screening of the title and abstract to establish eligibility. Information was acquired from the studies included in this systematic review using a data extraction form that had been pilot tested. The results obtained a total of 1341 articles selected through a search process by entering keywords in a predetermined database. Articles based on inclusion and exclusion criteria were selected, so that, seven articles were included in this study. Most of the studies indicated that EMR benefited health workers to give better clinical performances to the patients, improving quality-adjusted life year (QALY) of the patients, and reduce the mortality rates. In conclusion, implementing the EMR system may benefit health workers and increase their hospital performance. Keywords: electronic medical record; outcome; hospital; health workers
Validity of Predictive Markers for Post ERCP Pancreatitis Patients: A Single Centre Study Michael Tendean; Toar D. B. Mambu; Leonard A. Melatunan
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.51513

Abstract

Abstract: Endoscopic retrograde cholangiopancreatography (ERCP) is a proprietary procedure, endoscopic modality, and specialized procedure used to diagnose and treat disorders of the pancreatic and biliary systems. The incidence of reported post-ERCP complications varied among several studies including post ERCP pancreatitis (PEP), duodenal perforation, and cholangitis. In this study, the author would like to show certain intra procedural factors related to PEP incidence. This was a retrospective study of secondary data of patients undergoing ERCP procedures from 2017-2022 at Prof. Dr. R. D. Kandou Hospital, Manado. Length of procedure, cannulation on pancreatic duct, pancreatogram, double wire technique, and the use of certain common bile duct (CBD) stone retrieval techniques such as endoscopic papillary balloon dilatation (EPBD) were recorded and analyzed. The results showed that based on the analyzed data, the percentage of pancreas cannulation was 8%, pancreatogram 5%, double-wire technique 3%, and EPBD procedure 10%, Incidence rate of PEP in all ERCP procedures was 19%. Increased amylase/lipase enzymes were found in 13 of 24 patients (54%) who underwent cannulation; 8 of 16 patients (50%) who underwent pancreatogram; 4 of 9 patients (44%) who underwent double wire procedure; and 10 of 30 patients (33%) who underwent EPBD. This PEP could be caused by several risk factors during ERCP including cannulation, pancreatogram, double wire, and EPBD. Number of cannulation attempt could result in trauma to the ampulla. Pancreatogram could result in hydrostatic, chemical, and allergic injury. Any manipulation of the pancreas that caused trauma could trigger the incidence of PEP. Assessment of the occurrence of PEP was based on increases in lipase and amylase enzyme values by four times the normal value and tested 6 hours after procedure. We could reduce the incidence of PEP by providing prophylactic therapy before ERCP. In conclusion, PEP is the most common complication in ERCP procedures and can be risky in patients with high risk factors. In this study, factors that affecting the incidence of PEP are cannulation, pancreatogram, double wire and EPBD. Keywords: endoscopic retrograde cholangiopancreatography; pancreatitis; complications
Tiroidektomi Endoskopi Transoral dengan Pendekatan Vestibular Untuk Nodul Tiroid: Serial 12 Pasien Pertama di RSUP Prof. Dr. R. D. Kandou Riston R. Sitompul; Victor Pontoh; Marselus Merung; Christian Manginstar
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.51515

Abstract

Abstract: Transoral endoscopic thyroidectomy by vestibular approach (TOETVA), showed a comparable result to the conventional thyroidectomy, without any scar as the advantage. This study aimed to present the feasibility and safety of patients with solitary or multinodular goitre and or papillary thyroid carcinoma using TOETVA. This was a case series using 12 patients recorded undergoing TOETVA procedure. Eleven patients’ specimen obtained through FNAB resulted as benign nodule. In one patient, the nodule was malignant and unilateral, therefore, endoscopic isthmolobectomy was performed. Outcomes and measures included conversion to open conventional surgery, operative time, intraoperative blood loss, size of the thyroid gland, postoperative hospital stay, visual analogue scores, and postoperative complications. The results showed a total of 12 patients; all were women, aged 33-64 years. The size of thyroid nodules ranged from 2 cm to 7 cm. One patient got converted to open isthmus lobectomy. In this series, none of the patients were noted to have mental nerve injury but two patients developed anterior neck chin skin bruise. The mean postoperative VAS measurements were 2, 1, and no pain or 0, on the first, second, third, and seventh postoperative days, respectively. In conclusion, endoscopic thyroidectomy is feasible, safe, and comparable to open thyroidectomy and yields excellent aesthetic results. Keywords: endoscopic thyroidectomy; minimally invasive surgical procedures; thyroid neoplasms    Abstrak: Tiroidektomi endoskopi transoral dengan pendekatan vestibular (TOETVA), menunjuk-kan hasil sebanding dengan tiroidektomi konvensional, tanpa adanya bekas luka sebagai keuntungan. Penelitian ini bertujuan untuk menyajikan kelayakan dan keamanan pasien dengan penyakit gondok soliter atau multinodular dan atau karsinoma tiroid papiler menggunakan TOETVA. Jenis penelitian ialah serial kasus yang menjalani TOETVA selama Januari 2018 hingga Desember 2019 di RSUP Prof. Dr. R. D. Kandou. Terdapat 12 pasien tercatat menjalani prosedur TOETVA; 11 spesimen pasien diambil melalui FNAB dan menghasilkan nodul jinak. Pada salah satu pasien didapatkan nodul ganas unilateral sehingga dilakukan istmolobektomi endoskopi. Hasil dan tindakan termasuk konversi ke operasi konvensional terbuka, waktu operasi, kehilangan darah intraoperatif, ukuran kelenjar tiroid, rawat inap pasca operasi, VAS, dan komplikasi pasca operasi. Hasil penelitian mendapatkan 12 pasien, semuanya berjenis kelamin perempuan, berusia 33-64 tahun. Ukuran nodul tiroid berkisar 2 - 7 cm. Satu pasien diubah menjadi lobektomi terbuka. Tidak ada pasien yang tercatat mengalami cedera saraf mental, namun dua pasien mengalami memar pada kulit dagu leher bagian depan. Rerata pengukuran VAS pasca operasi ialah 2, 1, dan tidak nyeri atau 0, masing-masing pada hari pertama, kedua, ketiga, dan ketujuh pasca operasi. Simpulan penelitian ini ialah tiroidektomi endoskopi layak dilakukan, aman dan sebanding dengan tiroidektomi terbuka serta memberikan hasil estetika yang sangat baik. Kata kunci: tiroidektomi endoskopi transoral; minimal invasif; neoplasma tiroid
Exploring the Therapeutic Benefits of Silymarin Herbal Extract as a Supplement to Pulmonary Tuberculosis Treatment: A Comprehensive Review from Laboratory to Clinical Trials Muhammad I. D. Rakasiwi; Muhammad Taufik; Gusti C. Pamungkas; Muhammad Z. B. Amaanullah; Idham R. Dewantara
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.51870

Abstract

Abstract: Indonesia is ranked second in the number of tuberculosis (TB) cases with an incidence rate of 300 per 1000 population. A combination of antibiotics with a minimum six-month-administration regimen is an effective first line of TB treatment. Silymarin (Sm) is a plant extract which is known to have hepatoprotective and anti-microbial effects. This literature review aimed to discuss the potential of Sm in pulmonary TB treatment, starting from laboratory studies to clinical trials in humans. Studies on the use of Sm in tuberculosis literatures were obtained from a rapid systematic search in Pubmed and ScienceDirect databases. Supporting articles were searched based on specific keywords with inclusion criteria. The in vitro test showed immunomodulatory and bactericidal capacities of Sm against Mycobacterium tuberculosis. The in vivo test of Sm administration showed that Sm was able to increase the percentage of macrophage cells expressing the cytokines NF-κB and IFN-β. Sm had a bactericidal effect at levels >50 μM. The hepatoprotective character of Sm could prevent the increase in liver enzymes in mice receiving anti-TB drugs. Clinical trials showed that administration of Sm could prevent anti-tuberculosis drug hepatoxicity. In conclusion, silymarin has the potential to be an adjuvant therapy for the treatment of anti-TB drug-sensitive or resistant tuberculosis, as well as protection against the hepatotoxic properties of anti-TB drugs. Keywords: tuberculosis; silymarin; supplementation therapy; antituberculosis therapy
Efek Pemberian Suplementasi Kombinasi Vitamin C dan Albumin Terhadap Viabilitas Spermatozoa dalam Proses Sentrifugasi (Studi In Vitro) Maria K. A. Klau; Hudi Winarso; Florence Pribadi
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.52488

Abstract

Abstract: Sperm centrifugation is an important process to obtain good spermatozoa for assisted reproductive techniques. However, the centrifugation process has additional impacts such as increased reactive oxygen species (ROS) and oxidative stress affecting sperm viability due to damage of spermatozoa membrane. The use of vitamin C (ascorbic acid) can reduce elevated ROS levels, thereby protecting DNA and spermatozoa from damage caused by oxidative stress, meanwhile albumin can reduce oxidative stress and maintain the integrity of spermatozoa membrane. This study aimed to obtain the effect of combination of vitamin C and albumin on spermatozoa viability in centrifugation process. This was a true experimental in vitro study using post-test-only control design. There were four groups in this study, as follows: the control group (K); the treatment group (P1), centrifugation without vitamin C and albumin; (P2), centrifugation with vitamin C; and (P3), centrifugation with a combination of vitamin C and albumin. The Mann-Whitney test for each group showed significantly differences in spermatozoa viability (p<0.05) among them. The treatment group receiving supplementation with a combination vitamin C and albumin produced the highest viability after the control group. In conclusion, supplementation of combination of vitamin C and albumin is capable in maintaining spermatozoa in centrifugation process. Keywords: assisted reproduction technique; centrifugation; spermatozoa viability; supplementation    Abstrak: Sentrifugasi sperma merupakan proses penting untuk mendapatkan spermatozoa yang baik dalam keperluan teknik bantu reproduksi, namun proses sentrifugasi memberi dampak lain yaitu terjadinya peningkatan reactive oxygen spesies (ROS) dan stres oksidatif yang memengaruhi viabilitas spermatozoa akibat rusaknya membran spermatozoa. Pemberian vitamin C (asam askorbat) dapat menurunkan kadar ROS yang meningkat sehingga melindungi DNA dan spermatozoa dari kerusakan akibat stres oksidatif sedangkan albumin mampu mengurangi stres oksidatif dan mempertahankan integritas membran spermatozoa. Penelitian ini bertujuan untuk mengevaluasi pengaruh kombinasi vitamin C dan albumin terhadap viabilitas spermatozoa. Jenis penelitian ialah true experimental in vitro menggunakan post test only control design dengan pengamatan pada kelompok kontrol (K); kelompok perlakuan (P1) sentrifugasi tanpa vitamin C dan albumin; (P2) sentrifugasi dengan vitamin C; dan (P3) sentrifugasi dengan kombinasi vitamin C dan albumin. Hasil uji Mann-Whitney dari masing-masing kelompok menunjukkan viabilitas spermatozoa yang berbeda bermakna (p<0,05) antar satu sama lain. Kelompok perlakuan yang mendapat suplementasi kombinasi vitamin C dan albumin menghasilkan viabilitas tertinggi setelah kelompok kontrol. Simpulan penelitian ini ialah suplementasi kombinasi vitamin C dan albumin mampu mempertahankan viabilitas spermatozoa dalam proses sentrifugasi. Kata kunci: teknik bantu reproduksi; sentrifugasi; viabilitas spermatozoa; suplementasi
The Importance of Preoperative Evaluation to Predict the Outcome of Percutaneous Nephrostomy Ronald J. Datu; Eko Arianto; Ari Astram; Christof Toreh
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.52858

Abstract

Abstract: Percutaneous nephrostomy (PCN) is an invasive procedure equal to a grade 4 penetrating kidney trauma. It should be carefully considered whether has a greater benefit or risk. There are currently no parameters or scores to predict the outcome of nephrostomy in our center. This study aimed to conduct a review to find out whether there were parameters or scores that could be used to predict the outcome of nephrostomy. This research used relevant studies obtained from Clinical Key, PubMed, Semantic Scholar, Dimensions, and Science Direct published in the last 10 years and written in English. Studies on children and transplant cases were excluded. Studies that met the PICO criteria were selected. The results showed that of the 141 articles collected, and filtered with inclusion criteria, exclusion criteria, and PICO criteria, finally the remaining were three studies selected. The studies discussed about classification, SFU grading system, and complication of nephrostomy; significant variables affecting recoverability of renal function; patients’ characteristics and outcomes of double J ureteral stenting (DJS) and PCN; and 12-month-post-operative creatinine level change. Most patients who failed DJS had increased creatinine level. However, one of the indications for a nephrostomy was stenting failure. In conclusion, predictor factors that can affect the renal recovery after nephrostomy include kidney shape and size, pre-nephrostomy creatinine levels, urine output, state of infection, and degree of hydronephrosis. However, the evidence is still not enough. Further research is needed on the predictor factors for renal recovery after nephrostomy. Keywords:  percutaneous nephrostomy; hydronephrosis; kidney function; predictors
Hubungan Jenis dan Siklus Kemoterapi dengan Derajat Neuropati pada Pasien Keganasan Harlinda Haroen; Indriaty Gimon
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.53140

Abstract

Abstract: Antineoplastic chemotherapy agents in cancer treatment can cause peripheral neuropathy. Antineoplastic agents associated with chemotherapy-induced peripheral neuropathy include platinum-based drugs (carboplatin, cisplatin and oxaliplatin) and taxane (paclitaxel and docetaxel). This study aimed to evaluate the relationship between the type and cycle of chemotherapy with the level of neuropathy in malignant patients at Prof. Dr. R. D. Kandou Hospital, Manado, in 2022. The results obtained 43 cancer patients aged 18-65 who underwent chemotherapy, especially drugs from the platinum group (81.4%) such as oxaliplatin (62.8%). The majority of cases were colorectal adenocarcinoma (63%). Using the Toronto Score, the majority of subjects experienced mild neuropathy (55.8%), followed by without neuropathy (32.5%) and moderate neuropathy (11.6%). Although there was an indication of a relationship between the type of chemotherapy and the severity of neuropathy, the results were not statistically significant (p=0.069). In conclusion, there is no relationship between the type and cycle of chemotherapy with the level of neuropathy in cancer patients. Keywords: neuropathy; chemotherapy cycles; types of chemotherapy   Abstrak: Agen kemoterapi antineoplastik dalam pengobatan kanker dapat menyebabkan neuropati perifer. Agen antineoplastik terkait neuropati perifer yang diinduksi kemoterapi termasuk obat berbasis platinum (carboplatin, cisplatin dan oxaliplatin) dan taxane (paclitaxel dan docetaxel). Penelitian ini bertujuan untuk mengetahui hubungan jenis dan siklus kemoterapi dengan keparahan neuropati pada pasien keganasan di RSUP Prof. Dr. R. D. Kandou Manado pada tahun 2022. Hasil penelitian mendapatkan 43 pasien kanker berusia 18-65 tahun yang telah menjalani kemoterapi, khususnya obat berbasis platinum (81,4%) seperti oxaliplatin (62,8%). Jenis keganasan yang terbanyak ialah adenokarsinoma kolorektal (63%). Dengan menggunakan Skor Toronto, didapatkan mayoritas subjek mengalami neuropati ringan (55,9%) diikuti tanpa neuropati (32,5%) dan neuropati sedang (11,6%). Meski ada indikasi hubungan antara jenis kemoterapi dengan tingkat neuropati, hasilnya tidak bermakna secara statistik (p=0,069). Simpulan penelitian ini ialah tidak terdapat hubungan antara jenis dan siklus kemoterapi dengan tingkat neuropati pada pasien keganasan. Kata kunci: neuropati; siklus kemoterapi; jenis kemoterapi
Correlation between Doctor-Patient Communication with Patient Satisfaction and Loyalty Nancy S. Lampus; Dewi S. S. Wuisan
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.53161

Abstract

Abstract: Effective communication between doctors and patients has been recognized as a key factor in influencing the patient’s experience during treatment and will affect patient loyalty. This study aimed to investigate and analyze the correlation between doctor and patient communication with patient satisfaction and loyalty, in the context of health services. This was a cross-sectional study using a questionnaire as an instrument to collect data from several patients receiving outpatient treatment at the cardiovascular unit at XYZ Hospital. Data were analyzed multivariate using the PLS-SEM statistical method with SmartPLS®4 software. The results were obtained from 182 respondents who met the inclusion criteria taken in 2023 by purposive sampling with a questionnaire from individuals who had received cardiovascular outpatient services at XYZ Hospital. The five aspects of doctor communication skills were proven to have significant and positive effects. The strongest influence was shown in the empathy factor of communication by a doctor (R2 = 0.274; p-value 0.011; CI 0.086 – 0.479). This study proved the positive impact of patient satisfaction on patient loyalty at XYZ Hospital. From the findings of this study, managerial implications could be drawn for the development of doctors’ communication skills with patients, maintaining doctor quality, and strengthening the hospital image by providing the best services for patients. In conclusion, effective communication plays an important role in increasing patient satisfaction and loyalty toward health services in hospitals. It is necessary to maintain and improve skills in doctor-patient communication. Keywords: effective communication; patient satisfaction; patient loyalty
Hubungan Kegiatan Ekstrakurikuler dengan Psychological Well-Being Mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sam Ratulangi Felicia A. Gunawan; Hendri Opod; Lydia E. V. David
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.53197

Abstract

Abstract: Pre-Clinical Students tend to experience a decline in quality of life and well-being due to different responsibilities in curriculum, tasks, and demands during their studies. Extracurricular activities involve aspects of perseverance, empathy, and mindfulness, where these elements can prevent, and even enhance, an individual's psychological well-being (PWB). This study aimed to evaluate the correlation between extracurricular activities and PWB in pre-clinical medical students of Universitas Sam Ratulangi, Manado. This was a quantitative approach study employing data collection through the administration of the PWB scale (PWBS) questionnaire with 84 items developed by Ryff. The results obtained a total of 155 respondents participated in this study. The analysis did not reveal any correlation between participation in extracurricular activities and the dimensions of PWB. Albeit, a correlation was identified between the duration of involvement in extracurricular activities and specific dimensions of PWB (p<0.05). In conclusion, there is no correlation between extracurricular activities and PWB. However, there is a correlation between the duration aspect of involvement in extracurricular activities and PWB dimensions, especially the dimensions of positive relations with others and personal growth. Keywords: extracurricular activities; psychological well-being; duration aspect   Abstrak: Mahasiswa Program Studi Pendidikan Dokter cenderung mengalami penurunan kualitas hidup dan kesejahteraan karena adanya perbedaan dari segi kurikulum, tugas, dan tuntutan dalam menjalani studi. Kegiatan ekstrakurikuler merupakan suatu kegiatan yang melibatkan aspek ketekunan, empati, dan mindfulness, di mana aspek-aspek ini dapat mencegah penurunan, bahkan meningkatkan psychological well-being (PWB) seseorang. Penelitian ini bertujuan untuk mengevaluasi korelasi antara kegiatan ekstrakurikular dengan PWB pada mahasiswa pre-klinik Universitas Sam Ratulangi, Manado. Jenis penelitian ialah kuantitatif dengan metode pengambilan data menggunakan kueisioner PWB scale (PWBS) 84–items oleh Ryff. Hasil penelitian mendapatkan 155 responden yang terlibat dalam penelitian ini yang mengikuti kegiatan ekstrakurikuler. Tidak ditemukan adanya korelasi antara kegiatan ekstrakurikuler dengan dimensi PWB, tetapi terdapat korelasi antara aspek durasi keterlibatan ekstrakurikuler dengan dimensi-dimensi PWB tertentu (p<0,05). Simpulan penelitian ini ialah tidak terdapat hubungan antara ekstrakurikuler dengan PWB, tetapi terdapat hubungan antara aspek durasi keterlibatan ekstrakurikuler dengan dimensi PWB, terkhususnya dimensi positive relations with others dan personal growth.   Kata kunci: aktivitas ekstrakurikuler; psychological well-being; aspek durasi
Tingkat Depresi, Cemas, dan Stres pada Pasien Kanker yang Menjalani Kemoterapi Johanes A. Mastan; Linda W. A. Rotty; Harlinda Haroen; Cecilia Hendratta; Pearla Lasut
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.53335

Abstract

Abstract: Chemotherapy in cancer patients has psychological impacts which are depression, anxiety and stress. This study aimed to evaluate the levels of depression, anxiety and stress in cancer patients undergoing chemotherapy. This was a descriptive study with a cross-sectional design. Samples were obtained by using non-probability sampling with purposive sampling technique. Subjects were cancer patients undergoing chemotherapy at Prof. Dr. R. D. Kandou Hospital aged over 18 years old, not pregnant, and not having an infectious disease. Assessment of levels of depression, anxiety and stress using DASS-42. The results obtained 62 patients undergoing chemotherapy; 47 were women (75.8%). The median and interquartile age range was 52 (14.75) years and body mass index (BMI) was 22 (5.17), 42 patients having an income <3.5 million rupiahs (67%), 36 patients with duration of illness >1 year (58%) and the majority of patients (79%) were in marital status. Among subjects, 23% experienced depression, 40% experienced generalized anxiety disorder, and 21% experienced stress. In conclusion, patients undergoing chemotherapy can experience depression, anxiety and stress disorders. Keywords: depression; anxiety; stress; chemotherapy; cancer patients   Abstrak: Kemoterapi pada pasien kanker memiliki dampak psikis yaitu depresi, cemas, dan stres. Penelitian ini bertujuan mengetahui tingkat depresi, cemas, dan stres pada pasien kanker yang menjalani kemoterapi. Jenis penelitian ialah deskriptif dengan desain potong lintang. Sampel diperoleh menggunakan non-probability sampling dengan teknik purposive sampling. Subjek penelitian ialah pasien kanker yang menjalani kemoterapi di RSUP Prof. Dr. R. D. Kandou dengan usia di atas 18  tahun, tidak hamil, dan tidak sedang dalam pengobatan penyakit infeksi. Penilaian tingkat depresi, cemas, dan stres menggunakan DASS-42. Hasil penelitian mendapatkan­ 62 pasien yang menjalani kemoterapi; 47 pasien ialah perempuan (75,8%). Median dan interquartil range usia ialah 52 (14,75) tahun dan  IMT 22(5,17), dengan 42 pasien mempunyai pendapatan <3,5 juta rupiah  (67%),  36 pasien dengan lama sakit  >1 tahun (58%) dan sebagian besar pasien (79%) dalam status kawin. Sebanyak 23% pasien mengalami depresi, 40% gangguan cemas menyeluruh, dan 21% mengalami stres. Simpulan penelitian ini ialah pasien yang menjalani kemoterapi dapat mengalami gangguan depresi, cemas dan stres. Kata kunci: depresi; cemas; stres; kemoterapi; pasien kanker

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